Reading the title of this thread, the thought struck me: you know what'd be a really fun game?
Actual Space Sims.
Instead of houses, your Sims could have cabin/bunk-space aboard a starship, and get into all manner of hijinx as they go about their assigned tasks (perhaps with modifiers reflecting crew morale, discipline, and command structure. . .).
Party on the hangar deck! Woohoo!
"Party." --High Priest Harrar