I'd love to return to the Land of the Dead. I miss it very much. But I believe we should let the characters alone with their respective closure. I love Manny, but trying to rehash him in a sequel wouldn't work.
A prequel with Manny might work though.....
There's no earthly way of knowing which direction we are going. There's no knowing where we're rowing or which way the river's flowing. Is it raining? Is it snowing? Is a hurricane a-blowing? Not a speck of light is showing, so the danger must be growing. Are the fires of hell a-glowing? Is the grisly reaper mowing? Yes, the danger must be growing 'cause the rowers keep on rowing, and they're certainly not showing any signs that they are slowing. AAAGGHHH!!!