I went back and found/bought the Sam & Max Freelance Police: Special Color Collection, and a couple copies of the ONI Double Feature #10. (If anybody needs a copy) It only had the 1 page strip.
And yes while true, I do not have the super cool drawing (you lucky weasel) on the inside cover, I feel lucky to have found the collection period. I literally just stumbled across it and came on line to see where I remembered the strip from. So, now I have read parts of it and feel the need to track down a copy of the game. (Ebay.... ahhh).
Anyway, it was this boards high praise that introduced me to the characters. Before this I had seen a few episodes of the short lived cartoon series.