Well, I just got done playing for about an hour, havent beat it yet! I like it alot, I wont post anything about plot or puzzles, just the gameplay and style.
spoiler:The gameplay and the style rock. It feels great to play a new point and click adventure, full 3D, looking awsome, AND its Sam & Max. Lots to click on. I like the voices also. All around, I already love it.
You should be playing the game right now.