@Dark Lady: Yes.
@Tormentor: Orthodox Sith goals are to expand the Empire, first and foremost, and to deepen our understanding of the Dark Side. Revenge against the Republic and the Jedi is, of course, tempting, but there are other goals that come first.
When is this set?
I would recommend right after the Great Hyperspace War. The Sith are in tatters, in-fighting is rife etc etc...