What it's acting like, though with no mods etc it doesn't make a whole lot of sense... is when you have a bad / corrupt module.
I've had the same thing happen to me when I've tried to use the module editor and done something wrong re-building the thing to a compiled state. It loads and plays, but it's all black. You can hear sounds and access menus, but that's it.
Might try backing up your savegames and just completely uninstall/reinstall if playing with settings as Anakin suggested doesn't help. Then if it is some sort of file corruption it should be solved, though bear in mind that if all the saves you have contain the area information that's "bad", any save you load may well contain the problem, so a new game might also be required.