Whoa, that's some wicked teeth Thrik. We've come a long way with dental hygiene you know? Just pulling your leg (and not your teeth).
Set the volumes at diff levels (it's been awhile, but bkgrd music lower than speech and fx effects for example)?
Make sure you're using hardware based sound?
Enable subtitles...nevermind, don't think it's turned on during cutscenes
Check to see if anything's plugged into the soundcard (ie: gamepad)?
IRQ problems between different hardware components?
Update sound drivers?
Save more often?