I might just try this. My Xbox 360 play through died halfway through because I cannot for the life of me play first person shooters (even in RPGs), but I suspect my aiming would be much better wth a mouse. Wouldn't count on it, though. I really suck.
Am I the only one slightly put off by the voice of female Shepard? All I hear when she's talking is a silly cartoon my brother used to watch...