Tim Shafer will probably ultimately be the one who decides to continue a sequel game of Day of the Tentacle. I've always clamored for the story of Day of the Tentacle 2: Purple Tentacle's Revenge, just to follow the title similarities of the Secret of Monkey Island series.
The next generation adventure type game of this sort will probably be 3D or third person.
2D point and click interface is probably ancient history though I wouldn't mind seeing or playing either way.
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