The tutorial around Goodsprings is not a fair indication of the difficulty of the game. I went through Goodsprings now three times before finding a proper setup to actually have a chance to survive in the waste. First time, I was thinking hardcore was going to be a breeze until some Jackals along the way changed my mind.
About 9 to 10 hours in with this PC, no bugs, but one crash. Nothing major to me having lived with that type of thing in Fallout 3, save early, save often.