Update: So I ran the patch again but this time I went into the .ini file and I disabled fullscreen in both areas.
Interestingly, the game runs with the new resolutions. Unfortunately it does so in windowed mode (thought the window is the size of my display with the taskbar set to auto-hide). The GUI is off kilter a bit so you have to click low.
All-in-all, the difference between 1680x1050 and 1280x768 is not such that I'm willing tackle that learning curve, but I thought I would post this for others that are.