Absolutely loving the game despite its (many) glitches
UI is less than desirable, but no more clumsy than Oblivion's nested nightmare

I just favorite everything and auto-key 1-8 for my magic/weapon setups.
Was getting beaten down hard every second I turned a corner until I purchased a summon meat shield.. err, Flame Atronach. Definitely invest in this (or other conjuration) spell.. even for the melee classes. Makes encounters and combat much more manageable... hehe.
Smithing rocks, Alchemy limited in effect this round.. but the few you get can be awesome (and devastating). Mixed on the Enchanting mechanics. LOVE the idea on how you get the effects (disenchanting/breakdown).. not too thrilled on limiting what type of enchantment can go on what type of equipment. I'll be modding that for sure when the tools come around
Lots of fun stuff happening though.
Got caught in a clever little water trap.
Had a random dragon encounter on my way up the 7,000 step quest (as if things weren't hard enough.. stupid ice trolls

).
"Seems" I had a smashing good time after "winning" a drinking contest.. waking up in an entirely different city and all
Found (2) kewl books. One for a blind man (all blank pages.. hehe). And a nifty little "Zork"-like goto-page-such-n-such adventure
If the game continues to add little surprises and bits like this... yeah, I'll be in this for months on end.