No. There cannot be a Mass Effect 4. It would need a new name. There can't be a fourth ME, if it doesn't continue on Shep. Or the rest of the storyline for that matter.
EDIT: Just rewatched the ending...It kinda makes me not want to play the ME games again for some reason...it just kinda put the whole series down...
Last edited by Taak Farst; 03-11-2012 at 04:44 PM.