In a word.....no. To me it's really no more than a game and picking the DS/evil choices allows you to explore the various angles of the story more fully. I've abandonned both Ash and Kaidan and would have left both behind or saved both if the game had allowed. All about story options in the end.
Now, I want you to remember that no bastard ever won a war by dying for his country. He won it by making the other poor, dumb bastard die for his country.---Patton
There is no room in this country for hyphenated Americanism.---Teddy Roosevelt
I never forget a face, but in your case I'll make an exception.---Groucho
And if you all get killed, I'll piss on your graves.---Shaman Urdnot
How would you like to own a little bit of my foot in your ass.---Red Foreman