ooo ooo eee eee eeh!
Hi, a_monkey here!
I just reloaded Sam N Max and got it working great. Although under DOS. I suggest if you have WinXP, to make a FAT16 partition and put DOS on it, and dual-boot DOS/WinXP. Then when you want to run DOS games, you just select DOS.
I have a SBLive and use the SBLive2SB16 hack to get sound working under DOS.