Past the point of no return...The final threshold THE BRIDGE IS CROSSED SO STAND AND WATCH IT BURN!!
Oh wait... Wrong Point of no return.
The auto save IS the point of no return. Once it says 'AUTOSAVE! POINT OF NO RETURN" You can't go back into the regular levels of the game, which pretty much means once you help to free Lili from the restraints, no going back to camp and such. And to get to the lower floors of the asylum before the PONR, there's the elevator you used to get up to the upper floors, just go back in and you can go back down. HOWEVER, if your at Loboto's lab, there's another elevator around the walkway that'll take you to the asylum grounds.
"A few times in my life I've had moments of absolute clarity. When for a few brief seconds, the silence drowns out the noise and I can feel rather than think, and things seem so sharp and the world seems so fresh. I can never make these moments last. I cling to them, but like everything, they fade. I've lived my life on these moments. They pull me back to the present and I realize that everything is exactly the way it was meant to be."